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Drugs undergo four stages within the body: absorption, distribution, metabolism, and excretion.<span> Drugs can be absorbed through the skin.
</span><span>Or, some drugs can be inhaled as gases. Gases penetrate the lining of the esophagus and lungs very quickly, which allows the drug to enter the bloodstream. </span><span>
</span>Once a drug has entered the bloodstream,the blood throughout the body carries the substance with it.
The digestive system is involved in the process of metabolism of the drugs. and transform drugs into substances that can be expelled by the body. Enzymes within the liver break down the drugs.
1) closed circulation
2) The spleen can easily be damaged if someone suffers a sever injury to the stomach. When the spleen is damaged, it can cause pain in the abdomen, dizziness, and pain in the left shoulder.