The answer is; Sodium (Na+) and Potassium (K+) Ions
These cations are pumped out of the cell by Na+-K+ transmembrane protein pumps leaving the inside of the cell electronegative in relation to the extracellular matrix. This membrane potential is significant especially for neurons. Depolarization of the membrane enables transmissions of an impulse along the neurons.
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Answer:
In the human body, cells are the basic units of life. Groups of cells working together for a specific function form tissues. Organs are two or more tissues operating together. Even separate organs work together, forming body systems.