Explanation:
At position 12 of G protein Ras there is a normal amino acid attached to it called Glycine. Which make Ras protein a highly controlled protein. However, there is another amino acid called aspartate at 12 position which make Ras vulnerable by the formation of weak GTPase enzyme activity and GTP binding. Which prevent Ras from turning off. This the reason why aspartate in oncogenic. Furthermore, weak binding of GTP has influence because its binding can not be hydrolyzed.
Reference Research Paper
Morris, K. M., Henderson, R., Suresh Kumar, T. K., Heyes, C. D., & Adams, P. D. (2016). Intrinsic GTP hydrolysis is observed for a switch 1 variant of Cdc42 in the presence of a specific GTPase inhibitor. Small GTPases, 7(1), 1-11.
The answer for that is B large intestine
Answer:
How the sea serves us
> Many of the ecosystem services provided by the sea are threatened today by overexploitation, environmental pollution and greenhouse gases. Yet in many cases, how severely individual habitats are degraded and ecosystem services are impaired is just not known. Researchers are therefore attempting to assess the exact condition of marine ecosystems. Such analysis is important in order to plan concrete protection measures and to define critical limits and target values.
The bounty of the sea © Science Photo Library/Steve Gschmeissner/Getty Images
The bounty of the sea
> Since time immemorial we humans have been living with the seas and from their bounty. They provide us with food, mineral resources, transportation routes and other services. The climate-regulating effect of the oceans and the biochemical processes that take place in the sea are of fundamental importance. Today, some of these services are under threat, which i
1. Sensory Receptors: Detects changes of internal or external stimulus.2. Integrating center: sends signals to proper areas of the body regarding the stimulus.3. Effectors: Respond to stimulus to maintain homeostasis.
