Trepanation consisted on drilling a hole on a person's skull to relieve the pressure of blood after an injury and treat intercranial diseases. It is presumed this surgery exists from the Neolithic Age and has been done first by Egyptians, Greeks, Romans and Indians.
There are two definitions on which way you are saying stress.
pressure or tension exerted on a material object or a state of mental or emotional strain or tension resulting from adverse or very demanding circumstances.