In cell culture experiments, purified B cells expressing IgM can be induced to switch to producing IgE by stimulating them with
an antibody to CD40 (a stimulatory antibody) plus the cytokine IL-4. In an individual undergoing an immune response, these signals would normally be provided by:
The Tfh cells, present in the germinal center, are responsible for maturing and stimulating the class change of immunoglobulins (such as the change from IgM to IgE). This change could stimulate the new classes of immunoglobulins to act with stimulating antibodies to produce an immune response.
It is important to point out that the germinal center is the activated point of a lymphoid follicle that contains B and T lymphocytes, which act in the memory of the cells of the immune system.
Answer:Yes.. We. Should all be vaccinated to prevent bacterial meningitis
Explanation:bacterial meningitis is inflammation of the meninges.. It is a very fatal disease but can be prevented by vaccination which helps your body fight the bacterial organism to prevent infection
The cytochrome C oxidase has an active site which is the iron atom. When the cyanide binds to the iron it's inhibiting the enzyme activity, because it's physically avoiding the oxygen (substrate) from binding to the active site. This can lower the enzyme activity or stop it completely.