The answer is all of the above. This is so because any illegal drug is addicting because if the stimulants that effect your brain, and because of how they make the person feel... AKA they get high... Also, the person who takes the drug begins to "need" it to feel normal or better. this is called withdraw effects when the person has gone so long without taking an injection or something, then they start to become disorientated and feel bad until they take the drug again. this is part of the addiction. At first though, the person takes the drug and does not feel negative effects, so they most likely "sense" that it is OK to continue taking the drug despite known facts. Then after the short time, they do actually become fully addicted. But despite this, the addiction is usually most immediate.
The cerebellum is at the back of the brain, below the cerebrum. It's a lot smaller than the cerebrum. But it's a very important part of the brain. It controls balance, movement:
With high enough doses of alcohol, respirations stop first; which ultimately leads to death.
”Loose or lax ligaments in turn are not capable of supporting joints as effectively as healthy ones, making the affected individual prone to further injury as well as compensation for the weakness using other parts of the body. Afflicted individuals may improve over time and lose some of their juvenile hyperlaxity as they age. Individuals over age 40 often have recurrent joint problems and almost always have chronic pain. Back patients with ligamentous laxity in the area of the spine may also experience osteoarthritis and disc degeneration.
In the case of extreme laxity, or hypermobility, affected individuals often have a decreased ability to sense joint position, which can contribute to joint damage. The resulting poor limb positions can lead to the acceleration of degenerative joint conditions. Many hypermobility patients have osteoarthritis, disorders involving nerve compression, chondromalacia patellae, excessive anterior mandibular movement, mitral valve prolapse, uterine prolapse and varicose veins.”
