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Kisachek [45]
3 years ago
7

Which type of gene therapy results in alteration of the DNA of a gamete or a fertilized ovum?

Biology
1 answer:
larisa86 [58]3 years ago
7 0

Answer:

The correct option is: <u>e. Germline gene therapy</u>

Explanation:

The <u>germline gene therapy</u>, GGT is the <u>modification of the germ cells</u>. In this therapy, a functional gene is introduced into the genomes of the gametes. Such a modification of the germ cell results in all the cells of the organisms to get modified. This change can therefore be <u>passed on to the next generations.</u> Many countries such as Canada, Germany and Switzerland, have prohibited the use of the germline gene therapy on humans.

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assume that life on Mars requires cell potential to be 100mV, and the extracellular concentrations of the three major species ar
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From the information given:

The cell potential on mars E = + 100 mV

By using Goldman's equation:

E_m = \dfrac{RT}{zF}In \Big (\dfrac{P_K[K^+]_{out}+P_{Na}[Na^+]_{out}+P_{Cl}[Cl^-]_{out} }{P_K[K^+]_{in}+P_{Na}[Na^+]_{in}+ P_{Cl}[Cl^-]_{in}}      \Big )

Let's take a look at the impermeable cell with respect to two species;

and the two species be Na⁺ and Cl⁻

E_m = \dfrac{RT}{zF} In \dfrac{[K^+]_{out}}{[K^+]_{in}}

where;

z = ionic charge on the species = + 1

F = faraday constant

∴

100 \times 10^{-3} = \Big (\dfrac{8.314 \times 298}{1\times 96485} \Big) \mathtt{In}  \Big ( \dfrac{4}{[K^+]_{in}}   \Big)

100 \times 10^{-3} = 0.0257 \Big ( \dfrac{4}{[K^+]_{in}}   \Big)

3.981= \mathtt{In} \Big ( \dfrac{4}{[K^+]_{in}}   \Big)

exp ( 3.981) = \dfrac{4}{[K^+]_{in}} \\ \\  53.57 = \dfrac{4}{[K^+]_{in}}

[K^+]_{in} = \dfrac{4}{53.57}

[K^+]_{in}  = 0.0476

For [Cl⁻]:

100 \times 10^{-3} = -0.0257 \  \mathtt{In} \Big ( \dfrac{120}{[Cl^-]_{in}}   \Big)

-3.981 =  \  \mathtt{In} \Big ( \dfrac{120}{[Cl^-]_{in}}   \Big)

0.01867 =  \dfrac{120}{[Cl^-]_{in}}

[Cl^-]_{in} = \dfrac{120}{0.01867}

[Cl^-]_{in} =6427.4

For [Na⁺]:

100 \times 10^{-3} = 0.0257 \Big ( \dfrac{145}{[Na^+]_{in}}   \Big)

53.57= \Big ( \dfrac{145}{[Na^+]_{in}}   \Big)

[Na^+]_{in}= 2.70

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