Tight junctions are <u>cell junctions in areas that are subjected to great mechanical stress, such as the skin and heart muscles</u>
Explanation:
They are also called <u>exclusion junctions</u>. This is because they form very tight junctions between adjacent cells such that only very small molecules, like ions, can pass in between the intercellular spaces of the cells. This is why they are found in regions where very little leakage is needed such as the heart -where blood could leak out during pumping- or the skin where foreign material cannot be allowed into the body.
They are also favorable in high stress regions because they bound cells together giving them structural integrity because they limit the movement of cells and their membrane intergral proteins.