<span>True. Physical dependence on alcohol is more pronounced and
evident. This is because of the addictive factor of the alcohol, which similar
to some drugs, is a depressant. This substance usually inhibits any sympathetic
neural activity however disrupts the cognitive functioning of a person. </span>
Colchicine is a drug that can prevent the formation of microtubules. By blocking the synthesis of spindle microtubules, it will stop mitosis in cell division.
A traditional anti-mitotic medication called colchicine prevents mitotic cells from dividing during metaphase. It forms tubulin-colchicine complexes with soluble tubulin in an imperfectly reversible way, which bind to the ends of microtubules to stop the elongation of the microtubule polymer.
Colchicine is an alkaloid from the Colchicum autumnale plant that prevents microtubule polymerization, which is thought to be necessary for collagen production. This substance is therefore thought to function as an antifibrotic substance by inhibiting collagen production and deposition.
To learn more about Colchicine, refer
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I believe the answer is: No, depressed people in Eastern cultures do not devalue themselves like depressed people in Western cultures.
Eastern culture place a really high value on hardwork more than the western culture. So, people in eastern culture tend to see the act of succumbing to depression as being weak, which make them tend to deal it by working even harder to accomplish positive in life.
