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MrRa [10]
2 years ago
10

Explique que es coranavirus

Biology
1 answer:
Pepsi [2]2 years ago
6 0

oye no me lo de baja enviar y me tocó tomarle pantallazo de lo que estaba escribiendo y espero te ayude

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How does loseing laforin give you epilepsy ( please use lots of detail in the answer)
Deffense [45]
<span>Lafora disease is the most severe teenage-onset progressive epilepsy, a unique form of glycogenosis with perikaryal accumulation of an abnormal form of glycogen, and a neurodegenerative disorder exhibiting an unusual generalized organellar disintegration. The disease is caused by mutations of the EPM2A gene, which encodes two isoforms of the laforin protein tyrosine phosphatase, having alternate carboxyl termini, one localized in the cytoplasm (endoplasmic reticulum) and the other in the nucleus. To date, all documented disease mutations, including the knockout mouse model deletion, have been in the segment of the protein common to both isoforms. It is therefore not known whether dysfunction of the cytoplasmic, nuclear, or both isoforms leads to the disease. In the present work, we identify six novel mutations, one of which, c.950insT (Q319fs), is the first mutation specific to the cytoplasmic laforin isoform, implicating this isoform in disease pathogenesis. To confirm this mutation's deleterious effect on laforin, we studied the resultant protein's subcellular localization and function and show a drastic reduction in its phosphatase activity, despite maintenance of its location at the endoplasmic reticulum. 

I got my information from </span>https://www.ncbi.nlm.nih.gov/pubmed/14722920
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3 years ago
In order for chemical digestion to occur, what has to be mixed with the food?
siniylev [52]
Well in order for chemical digestion to occur period, a enzyme is needed.

In the mouth this enzyme is amylase
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Ludmilka [50]

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2 Points<br> What do bacteria have in common with the cells of other living organisms?
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Bacteria have cytoplasm and ribosomes which are common with the cells of other living organisms.

Explanation:

6 0
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