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Sauron [17]
3 years ago
14

Beta cells of the pancreatic islets of Langerhans act as glucose sensors, adjusting insulin output in response to blood glucose

levels. A porous silicon capsule was engineered as a delivery vehicle for porcine pancreatic beta-islet cells. The pore size in the capsule wall was optimized to allow for transport of glucose and insulin in and out of * indicates a significant difference compared to all other groups SS SS-TMSi SS-PCSi Platelet Deposition (Platelets/mm2 ) 2000 4000 6000 8000 * Silanated Phosphorylcholine (PCSi) * the capsule while protecting the islet cells from the host immune system. Pilot in vitro studies demonstrated effective glucose monitoring and insulin production by encapsulated beta islet cells. Upon implantation in a rat diabetes model, it was found that glucose was not monitored consistently and insulin was secreted below therapeutic levels. Bioluminescence imaging revealed that the beta islet cells were 96% viable in the capsules. What is the likely reason for the impaired function of the islet cell-silicon implants in vivo
Biology
1 answer:
LenKa [72]3 years ago
6 0

Answer:

Explanation:

The host's immune response to the transplanted graft, which is commonly exhibited as pericapsular fibrotic overgrowth (PFO), is one of the key causes of defective encapsulated islets in (PFO).PFO creates a barrier upon this capsule surface that inhibits and impedes oxygen and nutrients from entering, resulting in islet cell deprivation, hypoxia, and/or death. This host immune response was missing under in vitro circumstances, which explains why glucose sensing and insulin release were more efficient than in vivo circumstances. Nonetheless, utilizing nanoporous encapsulation or modifying the microcapsular shape and geometry can solve these issues.

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HELP PLEASE!!!!!!
allochka39001 [22]

Answer:

They probably use aerobic respiration.

Explanation:

A travel distance of 11.500 kilometers in 9 days covered by flying surely requires a lot of energy.

  • If cells are fermenting, the ATP (energy) they generate only comes from glycolysis, which produces 2 ATP molecules.

  • If they are using aerobic respiration, glucose is completely oxidized to CO₂ through glycolysis and the Citric Acid Cycle, and the electrons enter the electron transport chain to finally reduce oxygen into water. In the complete process, up to 36 ATP molecules are produced.

In sum, aerobic respiration is much more efficient to generate energy than fermentation, so it's probably the main metabolism of the flight muscles in bar-tailed godwits.

4 0
3 years ago
If someone were to load a firearm with the wrong-sized ammunition, what would likely be the end result? A, The shot would have a
morpeh [17]

Answer:

The correct answer is option C "There could be damage done to the firearm, and serious injury to the shooter".

Explanation:

There could be serious consequences of using the wrong ammunition when a firearm is being loaded. There could be damage done to the firearm, because the cartridge of the firearm could become lodged and could even explode. However, the most serious situation is the injury that the shooter could receive as result of the explosion. The data stamp of the ammunition must be checked to avoid this situation.

8 0
3 years ago
Large changes in temperature and acidity interfere with enzyme activity by _
ankoles [38]

Answer: Denaturing

Explanation: Enzymes are made of amino acids that are linked by bonds, amongst those bonds are hydrogen bonds that are very weak. High temperatures and low pH(acidity) breaks those bonds changing the molecular conformation of the enzymes. That way they denature and loss the ability to perform their functions. High temperatures and acidity alter the structure of their active site preventing the substrate from binding to them. While high temperatures denatures enzymes, low temperature renders them inactive.

7 0
3 years ago
PLEASE HELP!!!<br><br> *Note the answer is not C
Vladimir79 [104]

Answer:

B

Explanation:

Because the recessive c allele can be paired with the white rabbitś recessive c allele.

Could you perhaps mark me as brainliest? Thanks!

5 0
3 years ago
In what way do adaptations help the survival of a species?
ozzi

Adaptations help the survival of a species as "It increases the biodiversity of the species".

<u>Answer:</u> Option C

<u>Explanation:</u>

The phenomenon that support the organisms to find similar and favourable environment to acquire food, build home, satisfy with weather, feel safe and attract mates to produce more offspring in order to improve evolutionary fitness is called as an "Adaptation".

The three main forms of adaptations are behavioural, structural, and physiological adaptations that are based on the way how genetic variation get communicated. Many species have all those types of combinations. For an instance, behavioural adaptations are bird's calling and migration.

3 0
3 years ago
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