Fascilitated diffusion is an example of passive transport because a protein carrier helps pass a substance through the cell membrane. No energy is required to do this, which is why it is passive. (Active transport involves the expenditure of energy).
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Geo thermal : Nuclear reactions
Bio mass : plants
Solar : sun rays
Hydro power : Water
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Geothermal energy is also used to directly heat individual buildings and to heat multiple buildings with district heating systems. Hot water near the earth's surface is piped into buildings for heat. A district heating system provides heat for most of the buildings in Reykjavik , Iceland.
The major biomass sources currently used are sugar cane and corn to produce bioethanol , and rapeseed for biodiesel production. Other sources are also used such as sunflower seeds, soybean, canola, peanuts, jatropha , coconut and palm oil for biodiesel, and wheat, sugar beet, sweet sorghum and cassava for bioethanol
Conversion of energy from sunlight into electricity
Hydropower or water power is power derived from the energy of falling or fast-running water, which may be harnessed for useful purposes.
Some of the evidence comes from fossils, and some comes from studies that show how similar living things are to one another. By the 1930s, scientists had also learned about genes. As a result, they could finally explain how characteristics of organisms could pass from one generation to the next and change over time
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Explanation:
Pharmacophore (pharmacology) - The molecular framework responsible for a drug's biological activity. According to IUPAC — A pharmacophore is the ensemble of steric and electronic features that is necessary to ensure the optimal supramolecular interactions with a specific biological target structure and to trigger (or to block) its biological response.
Privileged structures are defined as molecular frameworks which are able of providing useful ligands for more than one type of receptor or enzyme target by judicious structural modifications.
1) The 1,4-dihydropyridine ring is present in many biologically important molecules that acts as an important scaffold for cardiovascular drug - a calcium antagonists and although it is technically not considered as a pharmacophore, it is considered as a privileged structure.
1,4-Dihydropyridine (DHP), belongs to the class of calcium antagonist that inhibits the influx of extracellular Ca+2 through the L-type voltage-dependent calcium channels.
A positional substitution in the 4-position is feasible in the heterocyclic ring which in turn culminates in various calcium channel antagonist activities and this heterocyclic ring is the common feature for various pharmacological activities such as anti-inflammatory activity, analgesic activity,
antihypertensive, antianginal, antitumor, antitubercular activity and antithrombotic .
Position on the heterocyclic ring binds to the L-type channel and also to N-type channel on membranes.
2.) The bioisosteres are not a suitable bioisostere for the traditional C-4 aryl or heteroaryl substitution which is necessary for calcium ion blockage thereby inhibiting it to function with the mechanism shared above.
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-"Cell - some cells are meant to do a certain job then destroy self
-Digestion of surplus cells by their own lysosomal enzymes
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