Answer: False
Explanation:
Long term alcohol use is dangerous in both the cases no matter the person is younger or older. Excess of any thing is bad the longer use of alcohol is damages the liver.
The long term consumption of the alcohol will lead to the severe detrimental effect on the body.
It can damage the central nervous system of the body, liver, increase the chances of anemia, et cetera.
<span>The limbic system is a collective term for a group of nuclei, tracts, and cortical areas lying beneath the neocortical surface that covers the brain and that surrounds the thalamus at the core of the forebrain.</span>
Answer and Explanation:
Ergotamine has been used for over 50 years and was the first specific drug to treat migraine attacks. Its therapeutic effect is due in part to its ability to contract the vessels. It is a vasoconstricting alkaloid used in migraine attacks, when treatment with non-steroidal anti-inflammatory drugs has no effect.
The mechanism of action of ergotamine is complex. The molecule has structural similarities to neurotransmitters such as seratonin, dopamine and adrenaline, and can therefore bind to various receptors and function as an inhibitor. Its use in the treatment of migraines is due to its vasoconstrictor effect of extracerebral intracranial blood vessels through their binding to the 5-HT1B receptor and inhibition of neurotransmitter binding.
Overuse of ergotamine may cause nausea, vomiting (to direct effects on the Central Nervous System in the vomiting centers) , malaise, headache, constriction of peripheral vessels and more severe effects such as ischemia of the extremities.
Ergotamine poisoning is called ergotism.
Ergotamine should not be used in patients with peripheral arterial or venous vascular insufficiency, ischemic heart disease, cerebrovascular disease, systemic infection and hypertension without effective control.
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