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Inhibitory neurotransmitters such as glycine and GABA make a postsynaptic cell harder to depolarize by allowing "an influx of Cl-".
<u>Explanation:</u>
The neurotransmitters which have inhibitory influence on the neuron are termed as "Inhibitory neurotransmitters". The major inhibitory neurotransmitters involve serotonin and gamma-aminobutyric acid (GABA) in the brain and brain stem (spinal cord) respectively.
GABA uptake is temperature and ion-dependent as require both
and
. Even glycine transporters are also members of the large family of
dependent neurotransmitter transporters. Both of them with the GABA transporters share approximately 50% sequence identity.