The answer is <span>a frameshift deletion at the beginning of the gene.
The frameshift deletion means that due to the deletion, the reading frame will be changed. Because of this, changed mRNA will be synthesized and translated into altered protein. It is known that codon is a triplet (a set of three nucleotides), that code for certain amino acid. The earlier in the sequence the deletion occurs, the protein will be more severely affected.
For example, if codons on RNA are THE BIG BAD DOG and the frameshift deletion happens on the first triplet (earlier in the sequence), the changed sequence will be TEB IGB ADD OG. If </span>the frameshift deletion happens on the third triplet (later in the sequence), <span>the changed sequence will be THE BIG ADD OG.</span> This way, if the<span> frameshift deletion occurs at the beginning of the gene,</span> the more codons will be changed and in turn, they will code different amino acids.
The answer to your question is B.Chromatin
The only disorder that cannot be represented using pedigree chart is sickle cell anemia. this because hemophilia, red-green color blindness, and duchenne muscular dystrophy are all X-linked traits. on the other hand sickle cell anemia is an autosomal recessive condition which cannot be represented in the pedigree chart since only sex linked traits are found this chart.
