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Fudgin [204]
3 years ago
12

why are the polio virus unable to reproduce if their DNA base sequence is different from the normal virus?

Biology
1 answer:
maks197457 [2]3 years ago
5 0

Answer:

When the virus infects a cell, the RNA genome enters the cell and programs it to make new virus particles. These virus particles are released from the cell and go on to infect new cells. In humans, poliovirus is ingested, and replicates in cells of the gastrointestinal tract.Poliovirus, the prototypical picornavirus and causative agent of poliomyelitis, is a nonenveloped virus with a single-stranded RNA genome of positive polarity. The virion consists of an icosahedral protein shell, composed of four capsid proteins (VP1, VP2, VP3, and VP4), which encapsidates the RNA genome (1).RNA viruses generally have very high mutation rates compared to DNA viruses, because viral RNA polymerases lack the proofreading ability of DNA polymerases. The genetic diversity of RNA viruses is one reason why it is difficult to make effective vaccines against them.

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The domestic cat genome contains 2.9×109 base pairs. The length of linker DNA in mammals is 50 base pairs. Approximately how man
IgorLugansk [536]

Answer:

Number of nucleosomes in 2.9 * 10^9bp is equal to 1.47 * 10^7

Explanation:

For wounding one nucleosome, total length of DNA required is equal to 146 bp

The length of  linker DNA in mammals is equal to 50 bp

Thus , the total length of DNA that confides between two nucleosome is equal to the sum of wounding length of DNA and the linker length

= 146 + 50\\= 196bp

Thus, in 196bp length of DNA, the total number of nucleosomes is equal to 1

Thus, number of nucleosomes in 2.9 * 10^9bp is equal to

\frac{2.9* 10^9}{196} \\1.47 * 10^7

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