Question

Outline the effect of the following mutations: TAG-> TAT TAC-> TCC

Answer 1

Answer:

TAG-> TAT >> sense mutation  

TAC-> TCC >> missense mutation

Explanation:

A sense mutation is a type of mutation that changes a stop codon into a sense codon, thus producing an elongated protein. The TAG codon (UAG in the RNA) is a stop codon, while TAT (UAU) encodes for tyrosine, thereby TAG-> TAT is a sense mutation. On the other hand, a missense mutation is a type of point mutation where a single nucleotide change generates a new codon which encodes a different amino acid. In this case, the TAC codon (UAC) encodes for tyrosine, while TCC (UCC) codon encodes for serine, and therefore TAC-> TCC is a missense mutation (Tyr to Ser mutation).