During T cell maturation, the t cells must pass two tests. first, immature t cells that can recognize MHC molecules are Selection. Second, immature t cells that recognize and bind to molecules normally found in the body are Activation.
Selection is the first test that T cells must pass. During this process, immature T cells that can recognize MHC molecules are selected. MHC molecules are found on the surface of cells and are involved in antigen presentation. When T cells come into contact with MHC molecules, they are able to recognize the molecules and begin the process of selection. During selection, the T cells that recognize MHC molecules are chosen over those that do not. This helps ensure that the cells that are selected are those that can properly respond to antigens.
The second test that T cells must pass is activation. During activation, T cells that recognize and bind to molecules normally found in the body are selected. These molecules are called self-antigens and can include proteins, carbohydrates, and lipids. When T cells come into contact with self-antigens, they are able to recognize the molecules and begin the process of activation. During activation, the T cells that recognize self-antigens are chosen over those that do not. This helps ensure that the cells that are selected are those that will not attack the body’s own cells.
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1. Both processes release energy
2. Both start with the breakdown of a nutrient (glucose)
3. Both yield byproducts
4. Both take place in a cell
5. Both involve pyruvate (pyruvic acid
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