It would be difficult for the United States for two reasons, the fact that none of the land was mapped other than the areas that previous voyagers had gone through, and the natural landscape of the area, and last, Native American Hostility.
Three examples: When pioneers would voyage to the west, there would often be encounters were they would be attacked by animals that had not been seen before, bears, sneaks, different wolves, and many more. They barely knew the natural resources of the area, such as food, etc.
The next example, no mapping, would be difficult because for the most part, they had no sense of navigation except for the few maps that had been made, even then, would be difficult to navigate.
Native Americans did not appreciate the pioneers coming into the land they considered their own, they resembled hostility and would even kill the civilians that would travel through the land, or capture them.
Hope this helps!! <3
In the 1962 book Silent Spring, Carson wrote how pesticides killed everything and should be called biocides because of that. Even though she had her worries about acute pesticide poisoning, she was really alarmed about slow pesticide poisoning of everything, like humans and plants. Her intentions on the book were to educate people about pesticide risks, trying to transform the "myth" of pesticides into reality for the masses.