Answer:
The answer is reciprocal chromosomal translocation
Explanation:
The Philadelphia chromosome (Ph) is the truncated chromosome 22 generated by the reciprocal translocation t(9;22)(q34;q11) and was first identified in 1960 in a patient with CML [3]. Translocation of the proto-oncogene tyrosine-protein kinase (ABL1) gene located on chromosome 9 to the breakpoint cluster region (BCR) gene located on chromosome 22 results in a BCR-ABL1 fusion gene on the Ph [4, 5]. Three BCR-ABL1 fusion gene hybrids encode BCR-ABL1 protein isoforms p210, p190, and p230, which have persistently enhanced tyrosine kinase (TK) activity. These aberrantly activated kinases disturb downstream signaling pathways, causing enhanced proliferation, differentiation arrest, and resistance to cell death [6, 7]. Tyrosine kinase inhibitors (TKIs) targeting the BCR-ABL1 protein are the most successful targeted therapy for Ph-positive leukemia.
<span>Mitosis is the cell division that happens in all cells in the human body except sperm and egg cells. They produce diploid cells. While meiosis on the other hand is responsible for the cell division of the gametes, spermatogenesis (sperm cells) and oogenesis (egg cells), such haploid cells. </span>
Animals that have a backbone are called Vertebrates. (Mammals, for example.)
The movement of a snake is referred to as “Slithering.”
The Stapes is the smallest bone in the human body.
mark as brainliest if i helped. good luck :) !!
Answer: ok ill help:
1. over population happens when too many babies are born and the place gets crowded
2. same thing happens is too many immigrants go to 1 place E.G UK
