They sailed from Plymouth, on the southern coast of England.
What exactly is the question here?
I believe the correct answer to this would be A). Epidemics
Answer:
Option: B. England using the Navigation Acts to control colonial trade
Explanation:
England dominated the trade by forcing taxes on American colonies. England believed in the mercantilist policies, which let the colonies supply raw materials to create wealth in their mother country. The Navigation Act of 1651 allows to trade with Britain and prevent colonists trade with other countries.