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inn [45]
3 years ago
5

Most cells in the human body utilize Ca2 ions as enzymatic cofactors and/or second messengers for signaling processes. What chal

lenges, if any, does the presence of these ions pose for the use of taxol for treating human cancers?
Biology
1 answer:
kodGreya [7K]3 years ago
3 0

Answer:

Taxol alters cytosolic calcium signaling by opening mitochondrial pores

Explanation:

Taxol is an antimitotic (i.e., cytotoxic) agent used in chemotherapy to kill cancer cells. Taxol is an antimitotic drug that has been successfully used in different types of cancer including ovarian cancer, breast cancer, pancreatic cancer, sarcoma, etc. Recently, it has been shown that Taxol may induce rapid cytosolic calcium (Ca2+) response by producing a decrease in mitochondrial membrane potential associated with the loss of mitochondrial Ca(2+). In consequence, it has been proposed that the side effects of chemotherapy might be associated with the action of cytotoxic agents such as Taxol which alters mitochondrial function and Ca(2+) signaling cascade.

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2. Many people believe that
gladu [14]

Answer:

A mutation is simply an error in the copying of DNA it generally does not have major effects. Mutations are changes in the DNA sequence.  

Tumors form by an uncontrolled error in a stage of mitosis that continue to generate cells that aren't correct and eventually lead to tumors.

Explanation:

4 0
3 years ago
Assuming a typical monohybrid cross in which one allele is completely dominant to the other, what phenotypic ratio is expected i
IgorC [24]

Answer:

Assuming the dominant allele is represented as A, and the genotype as AA and the recessive as a, and genotype as aa; then the F1 will produce the offispring. Aa, Aa, Aa,Aa in ratio: 1:1:1:1:1

This shows the dominance of allele A.

However if two of  the F1 generation are crossed then:

The  F2 is AA,Aa,Aa,aa the phenotypic ratio is

                        3   ;     1

W<u>hile the Genotypic ratio is ratio;</u>

<u>   1AA : 2Aa Aa; 1aa(1 ;2;1)</u>

Explanation:

8 0
4 years ago
Which best describes plant classification?
mario62 [17]
If the question goes like this: Which best describes plant classification? <span><span>
A.      </span>Nonvascular plants are grouped into seedless and seeded plants. </span> <span><span>
B.      </span> Seedless plants are grouped into gymnosperms and angiosperms.</span> <span><span>
C.      </span>Gymnosperms are grouped into monocots and dicots. </span> <span><span>
D.      </span> Angiosperms are grouped into monocots and dicots.</span>   <span>

The best answer will be letter D. Angiosperms are grouped into monocots and dicots.</span>     Botanists grouped or classified together according to its characteristics.

see attached file for more information about classification of plants.


Download docx
6 0
3 years ago
The pharmacy has sent up lasix for a patient. the bottle is labeled “10 mg per ml.” the physician’s order calls for a dose of 40
bezimeni [28]

The answer is 4ml

Lasix is made of furosemide, a diuretic drugs that frequently used. To know the volume of drug needed, you need to divide the dose needed by the drug concentration. The dose gien is 40mg per dose while the concentration of the drug is 10mg/ml. The drug administered per doses would be: 40mg/ (10mg/ml)= 4ml

3 0
3 years ago
The density of ice is actually less than that of liquid water above 4c explain why
Olenka [21]
Water expands as it freezes, so ice generally has more oxygen in it than liquid water, making it denser.
6 0
3 years ago
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