Answer: from the tea to the air
B. Get Energy, Maintain Health, and Reproduce
I think...
A murine model of hemorrhagic refractory shock showed improved post-resuscitation survival time with adjuvant cytosolic energy replenishment.
<h3>
Objective:</h3>
- Resuscitation of a patient with refractory hemorrhagic hypovolemic shock (HS) is difficult.
- HS is linked to severe reductions of cellular energy nucleotides, which can result in cardio-circulatory arrest and mortality.
- Vasopressors, most often norepinephrine, are typically briefly supplied to control a persistent hypotension that is not rectified by intensive resuscitation attempts in order to avert an impending cardio-circulatory arrest.
<h3>Method</h3>
The following five groups of 10 each were randomly assigned to 50 male Sprague-Dawley rats:
- HS/conventional resuscitation (CR), HS/CR+norepinephrine, HS/CR+vasopressin, HS/CR+vesicles, and HS/CR+ATPv.
- ATPv, which are highly fusogenic lipid vesicles encasing ATP, were used to directly replace the cytosol with ATP.
- Direct cytosolic ATP delivery is made possible by the instantaneous fusion of the ATPv with the cell membrane.
- The study's endpoint was established as the post-resuscitation survival period.
<h3>Results:</h3>
The SI and MAP showed that all animals experienced the same kind of shock. According to the long-rank Mantel-Cox test and Kaplan-Meier survival curves, the median post resuscitation survival periods were as follows: HS/CR+Nor epinephrine = 35.5 min; HS/CR+Vasopressin = 20 min; HS/CR+Lipid Vesicles control = 88.5 min; and HS/CR+ATPv = 158.5 min
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<u>brainly.com/question/26846478</u>
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Answer:
6 months
Explanation:
First, we must remember that doxycline has an effect only on nematodes, but it cannot effectively prevent microfilariae presented before treatment in the blood of the infected. What we can conclude from this is that it is possible that microfilariae grow and develop, however they will not be able to reproduce, since W. bancrofti is completely dependent on Wolbachia for replication. With that, the microfilariae are running out of time and with about 6 months the patients are free of any trace of microfilariae. So we can conclude that 6 months is the longest time that microfilariae survive in circulation.
