How enzymes inhibitions studies in the formulation and development of drugs

Biology

1 answer:

lesya [120]2 years ago

7 0

Answer:

Enzyme inhibitors may alter the elimination rate of a particular drug or inhibit detoxication pathways

Explanation:

An enzyme inhibitor is a chemical compound capable of binding to an enzyme in order to reduce its activity. An enzyme inhibitor may bind to an active site and thus decreases the rate of reaction (direct inhibition). Enzyme inhibitors may act 1-to Inhibit detoxification enzymes and 2-reduce the elimination rate of enzyme drugs, thereby having dose-dependent toxicity effects. For example, many medicines are based on the inhibition of Cytochromes P450 (CYPs) proteins, which are a superfamily of enzymes required for drug metabolism.

You might be interested in

Discuss how the concept of "survival of the fittest" was developed and what it means.

adelina 88 [10]

Explanation:

Survival of the fittest is a phrase that originated from Darwinian evolutionary theory as a way of describing the mechanism of natural selection.In On the Origin of Species, he introduced the phrase in the fifth edition published in 1869, intending it to mean "better designed for an immediate, local environment".

4 0

2 years ago

Suppose there are two homologous chromosomes. Each chromosome contains a single mutant allele in different parts of the chromoso

Harlamova29_29 [7]

Answer:

Cross overs can lead to formation of chromosome pairs that have no mutant allele.

Explanation:

Cross overs can lead to formation of chromosome pairs that have no mutant allele.

For example -

Suppose "X" is a mutant allele and "x" is a mutant free allele.

Now when two homologous chromosomes contains a single mutant allele in different parts of the chromosome are crossed the following offspring are produced

X x

X XX Xx

x Xx xx

"xx" is a mutant free genotype.

Thus, crossing over can create a single mutation-free chromosome

8 0

2 years ago

A liter is the same as a ____. A) cubic centimeter. B)cubic decimeter C)cubic meter D)cubic decameter

Sunny_sXe [5.5K]

A. Cubic centimeter

6 0

3 years ago