In the following orbital the lone pair on each N atom is present:
N1: sp3,
N2: p,
N3: p,
N4: sp2,
N5: sp2
Sitagliptin is an anti-diabetic drug used to treat type 2 diabetes and is marketed under the brand names Januvia and others. One carbon atom has no pi bonds, while the first nitrogen atom is linked to two hydrogen atoms. It thus possesses sp3 hybridization.
The second nitrogen atom possesses a single pair of electrons and is bound to three other atoms. It is hence sp2 hybridized. The nitrogen atoms in positions 3, 4, and 5 have sp2 hybridization.
The lone pair of nitrogen in the first nitrogen atom is in the sp3 orbital. The second and third nitrogen atoms' only pair of electrons are in p-orbitals. The fourth and fifth nitrogen atoms' lone pair of electrons are in sp2 orbitals.
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Answer:
Explanation: A megadose refers to a high dose of a vitamin such as 10 to 20 times the RDA.
The evaluation for neural tube defects should be included in a patient that took carbamazepine throughout the first trimester of pregnancy.
<h3>What is Carbamezepine?</h3>
Carbamazepine may be characterized as an anticonvulsant medication often operated for the remedy of epilepsy and neuropathic ache provoked by diabetes.
Carbamazepine has newly been determined to have a proliferation threat of genetic malformations and neurodevelopmental irregularities, at the time of pregnancies.
Therefore, the evaluation for neural tube defects should be included in a patient that took carbamazepine throughout the first trimester of pregnancy.
The complete question is as follows:
- Evaluation of fetal hydramnios.
- Evaluation for neural tube defects.
- Evaluation of cardiac malformation.
- Chromosomal assessment for down syndrome.
To learn more about Carbamazepine, refer to the link:
brainly.com/question/4248303
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Answer:
Perdón, pero no hablo español.
Explanation:
The practice of pharmacy requires excellent knowledge of drugs, their mechanism of action, side effects, interactions, mobility and toxicity. ... Pharmacists, therefore, are the experts on drug therapy and are the primary health professionals who optimize the use of medication for the benefit of the patients.
