Answer:
Namely by making WW3 unthinkable. Without nuclear weapons in the picture, a massive conventional war between the United States and Soviet Union would have been virtually inevitable. The very reason it was a "Cold War" at all is thanks to nuclear weapons.
Explanation:
The opposite word for secede is untie
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One very famous, perhaps the most famous way was through improvised vaccination. Specifically, George Washington ordered his healthy men to be injected with substance taken from the wounds of the sick men during a smallpox infection.
A risk was that those men would get sick just like the the sick men did, but the the potential reward would be that they would get sick in a controlled way and that they would be able to fight this disease.