Answer:
This question is incomplete as it lacks the base sequence of the normal and sickle cell hemoglobin. The base sequence are as follows;
normal: GGG CTT CTT TTT
sickle: GGG CAT CTT TTT
ANSWERS:
normal mRNA: CCC GAA GAA AAA
normal tRNA: GGG CUU CUU UUU
sickle amino acid: Proline- Glutamate- Glutamate- Lysine
sickle mRNA: CCC GUA GAA AAA
sickle tRNA: GGG CAU CUU UUU
sickle amino acid: Proline- Valine- Glutamate- Lysine
Explanation:
Transcription is the process whereby a DNA base sequence is used as template to synthesize a mRNA strand, while translation is the process whereby a mRNA base sequence is used to synthesize an amino acid sequence (protein).
- In this question, the DNA base sequence for normal hemogoblin and the base sequence for the sickle cell hemogoblin is given as follows;
normal: GGG CTT CTT TTT
sickle: GGG CAT CTT TTT
* The transcription of both sequences using complementary base pairing is as follows:
normal DNA: GGG CTT CTT TTT
normal mRNA: CCC GAA GAA AAA
Sickle DNA: GGG CAT CTT TTT
Sickle mRNA: CCC GUA GAA AAA
* The translation of both sequences using the genetic code is as follows:
normal mRNA: CCC GAA GAA AAA
normal amino acid: Proline- Glutamate- Glutamate- Lysine
sickle mRNA: CCC GUA GAA AAA
sickle amino acid: Proline- Valine- Glutamate- Lysine
