Answer:
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Answer:Smallpox and vaccination are intimately connected. Edward Jenner developed the first vaccine to prevent smallpox infections, and this success led to the global eradication of smallpox and the development of many more life-saving vaccines.
Explanation:
In September of 1787, it was sent to the states for ratification. Nine of the 13 states would have to ratify it for the Constitution to become effective for those ratifying states. The future was not certain at all—a debate began among the states over ratification.
