Answer:
Apoptosis also plays a key role in human development. For instance, as we saw in the introduction, your hand started out as a paddle-like block of tissue when you were an embryo. The block was “carved” into fingers by apoptosis of the cells in between the developing fingers.
Explanation:
If a cytosine base is substituted for by a thymine base in a DNA segment during DNA replication, the sequence could code for the wrong amino acid during translation.
The change in the sequence of DNA is known as mutation.
When a base substitution occurs in the sequence of a DNA during replication, the genetic information in the region where the substitution occurred becomes compromised.
During transcription, the process of encoding genetic information on DNA into RNA, the base substituted is also transcribed along. If cytosine is substituted by thymine, adenine is transcribed instead of guanine.
During the translation of the genetic codes, the wrong amino acids might end up being translated due to the substituted base, leading to a faulty protein.
More on mutation can be found here: brainly.com/question/4347425
Answer:
The correct answer would be - MMR would be hindered because both strands would be unmethylated and both would appear as new DNA strands and it would not be able to determine which strand has the error
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Explanation:
In gene expression or DNA replication, the enzyme responsible for the synthesis of DNA from nucleoside triphosphate causes errors sometimes such as mismatch base pair that result in a change in genetic makeup.
For MMR, the DNA template and the strand formed required easily to be differentiated. As the newly synthesized strand is unmethylated and the DNA template strand is methylated results in DNA remain hemimethylated for a very short period.
After MMR, DNA adenine methylase enzyme that transfers a methyl group to the adenine of the sequence 5'-GATC-3' daughter strand formed.
Mutated DAM or DNA adenine methylase will not be able to transfer methyl group which leaves both template and daughter strands unmethylated and mismatch repair would be hindered as it will not be able to identify.
The scientific study of abnormal behavior in an effort to describe, predict, explain, and change abnormal patterns of functioning
