Answer is D:) Just took the test
Answer:
c. in renal dysfunction, dosage reduction is necessary to avoid seizures
Explanation:
Imipenem is an antibiotic which is given in combination with cilastatin. It is used to treat pneumonia, joint infections, urinary tract infections, sepsis etc. It kills bacteria by interfering with its cell wall formation process. It is metabolized in kidney reducing its half life so cilastatin is given with it to halt its renal metabolism.
Imipenem belongs to carbapenem family of antibiotics. Carbapenem antibiotics can cause seizures specially in people with nervous system disorders or renal failure. Dose must be reduced in patients with renal (kidney) dysfunction otherwise patient's kidneys will be damaged more and since they are already in weak state, it can prove dangerous to the patient.
Of the following given choices;
A. a lack of electrolytes in the brain
B. fatty mitochondria
C. two nuclei in some neurons
D. progressive deterioration of the myelin
The answer is D.
Musciplte sclerosis is an autoimmune condition in which the immune system of the subject attacks the nervous system. Specifically, the immune system attacks the myelin sheath of neurons as though they are foreign hence causing them damage. Myelin sheath protects the neurons and also allows impulses to pass along the axon much quicker than it would be without the sheath.
