Checkpoint proteins at the G1, G2, and M phases of the cell cycle monitor whether crucial cellular process have been completed c
orrectly and the cell cycle can proceed. A mutation in a checkpoint protein can lead to cancer by resulting in the checkpoint protein not functioning properly. Which of the following could be a result of the improper functioning of a checkpoint protein in a cancer cell? a. Cell division stops.
b. The cell reverts to interphase.
c. There is uncontrolled cell division.
d. The cell dies.
There is uncontrolled cell division that result in the improper functioning of a checkpoint protein in a cancer cell because checkpoint protein monitors and control the the process of cell cycle. If mutation occurs in this checkpoint protein, the cycle is no longer in control which leads to the uncontrolled cell division and we also know that cancer is a disease which occurs due to uncontrolled division of the cell.
Taxol's primary action is to bind to microtubules, especially β-tubulin, and prevent their depolymerization, thereby stabilizing mitotic spindle during anaphase of mitosis which leads to arrest of cell cycle.
