Part 1.
The correct answer is option 2.There are two alleles for freckles.
According to the condition of the occurrence of the freckles, it can be concluded that the freckle is an autosomal dominant condition. The freckle can only be inherited, if there is at least one dominant allele in any of the parent. If both the individuals are heterozygous for the trait, they can produce an offspring without freckle by passing down the recessive alleles to the progeny. So, the freckles are controlled by two alleles, which can be either dominant or recessive.
Part 2.
The correct answer is option 4. P generation and F2 generation.
In this case, it is given that true bred homozygous recessive plant is crossed with true bred homozygous dominant plant. The true bred recessive plant always shows the recessive phenotype. When true bred homozygous recessive plant is crossed with true bred homozygous dominant plant, the F1 generation would produce all the heterozygous individual and exhibit dominant phenotype. When the F1 generation is self crossed, it result in 75% dominant phenotype and 25% recessive phenotype.
A possible cross for this case is given in the picture.
Osteoporosis is a condition that makes bones more porous, which makes them more brittle and likely to break.
It is directly connected<span> with the lumen of the endoplasmic reticulum.</span>
This patient both has left-sided heart failure and right-sided heart failure. In left-sided heart failure, this patient exhibits increasing shortness of breath on exertion as well as three pillow orthopnea which indicates pulmonary congestion. This is because of pooling of blood in the pulmonary circulation. Bipedal edema, in this patient is a grade 2 bipedal edema, reflect right-sided heart failure as there is pooling of blood in the systemic circulation, causing transudation in the most dependent areas of the body.