The clue word "however" almost always indicates a "contrast". This is because when using this word, the writer can on one hand agree with what he or she is saying, but offer a different point of view to be considered.
The answer would be C, as it is the only one that makes sense when you read it. Hope this helps.
B, not sure if it's right.
Answer: Hyphen means that Joseph is not able to take on such a big responsibility such as taking care of Jupiter. I hope this helps!
Explanation: