Well, i think the answer would be : B. Stubborn and confident
Sherlock holmes was always known around his peers for his intelligence.
Many of his stubbornness acts that could resulted in awkward situations that many readers could find humorous
Hope this helps <span />
The error that makes the sentence wrong is the word of "Although." It makes the sentence like a fragment. It looks like it need another clause to make it a complete one.
1. heredity
2. environment
3. peers
4. culture
5. media