His heart isn't pumping adequately to remove the water from his body due to his weight gain because it takes more for your heart to work correctly if your are over weight
Answer:
the pathway will be under-expressed.
- the alpha subunit helps to bind with either GDP or GTP. when the α subunit is bound with GDP, it will be bound to β and γ subunits and thus forms an inactive state for G-protein.
- when the alpha subunit binds with the GTP, it becomes activated and dissociates β and γ subunits.
if G-protein Coupled Receptor is unable from dissociating β and γ subunits, then the pathway will go under expression.
The chemical qualities of the alpha subunit allow it to bind easily to one of two guanine subunits, GDP or GTP. The protein thus has two functional formations. When GDP is bound to the alpha subunit, the alpha subunit remains bound to the beta-gamma subunit to form an inactive trimeric protein.
G-proteins, cAMP, and Ion Channel Opening. The alpha subunit activates adenylate cyclase, in purple, and loses GTP. Adenylate cyclase converts ATP to cyclic AMP, which then activates Protein Kinase, shown in blue. Protein Kinase phosphorylates an ion channel, letting sodium ions rush into the cell.
As a result of the ligand binding to its site on the G-protein-linked receptor, A) the G-protein changes conformation and GTP replaces the GDP on the alpha subunit. ... Inactivation of the alpha subunit occurs when its own phosphorylase activity removes a phosphate from the GTP.
Answer:
The correct answer is True
Explanation:
<u>The first step in glycogen synthesis (glycogenesis) is the phosphorylation of glucose to form glucose-6-phosphate</u>, which is catalyzed by hexokinase. [This step is also the first step in the glycolytic pathway]. Glucose-6-phosphate is then isomerized to glucose-1-phosphate by the action of phosphoglucomutase. This glucose-i-phosphate is then converted to glycogen by glycogen synthase.
