Answer:
while mesoamerican civilization knew of the wheel and basic metallurgy, the technologies became important. the earliest complex civilization was Olmec culture, which inhabited the gulf of mexico. (known for Olmec, Maya, Zapotec, Teotihuacan, Mixtec, and Mexica (or Aztec)
The event that marked the end of the Roman Republic is often attributed to the defeat of Marc Antony in 31 BC at the Battle of Actium which ended the period of civil war.