<span>he Streptococcus pneumoniae capsule is vital for virulence and may inhibit complement activity and phagocytosis. However, there are only limited data on the mechanisms by which the capsule affects complement and the consequences for S. pneumoniae interactions with phagocytes. Using unencapsulated serotype 2 and 4 S. pneumoniae mutants, we have confirmed that the capsule has several effects on complement activity. The capsule impaired bacterial opsonization with C3b/iC3b by both the alternative and classical complement pathways and also inhibited conversion of C3b bound to the bacterial surface to iC3b. There was increased binding of the classical pathway mediators immunoglobulin G (IgG) and C-reactive protein (CRP) to unencapsulated S. pneumoniae, indicating that the capsule could inhibit classical pathway complement activity by masking antibody recognition of subcapsular antigens, as well as by inhibiting CRP binding. Cleavage of serum IgG by the enzyme IdeS reduced C3b/iC3b deposition on all of the strains, but there were still marked increases in C3b/iC3b deposition on unencapsulated TIGR4 and D39 strains compared to encapsulated strains, suggesting that the capsule inhibits both IgG-mediated and IgG-independent complement activity against S. pneumoniae. Unencapsulated strains were more susceptible to neutrophil phagocytosis after incubation in normal serum, normal serum treated with IdeS, complement-deficient serum, and complement-deficient serum treated with IdeS or in buffer alone, suggesting that the capsule inhibits phagocytosis mediated by FcÎł receptors, complement receptors, and nonopsonic receptors. Overall, these data show that the S. pneumoniae capsule affects multiple aspects of complement- and neutrophil-mediated immunity, resulting in a profound inhibition of opsonophagocytosis.</span>
I think the answer to you r question is C. bc with no sunlight at the bottom the temp is affected. Also I looked up photosynthesis and it said that scientist have found this at the bottom of the ocean so it in fact does perform more photosynthesis
What do you think?
Biological evolution is the result of genetic changes in a population of a species
ANSWER: interspecific competition
Answer:
The correct answer is a tRNA brings over the correct amino acid by using the anticodon to match to mRNA during translation
Explanation:
tRNA or Transfer RNA play an important role during the translation process.tRNA contain anticodon that interracts with the codon of mRNA molecule with the help of Ribosome to bring the amino acid to its own acceptor arm. The amino that is brought to acceptor arm of tRNA is specific for the codon present in mRNA.
tRNA then moves to the P site and a new tRNA bind to the A site of ribosome and brings a new amino acid that form peptide bond with previously generated amino acid. Then process continue untill the tRNA recognizes a termination or nonsense codon
