Answer:
Government regulations are established when a problem that may be detrimental to universal health or national security is found. Take for example, the <em>Federal Bureau of Investigation</em>, that regulates security in the public, and take note and act upon any suspects that can be hazardous to the people.
So where there is a public problem, the government will help to solve and prevent any future problems of it (to the best of it's ability of course.)
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The reason that led to the rise of the domestic slave trade was the regional specialization in labor production. The South had a much higher demand of slaves for the labor-intensive cotton plantations. This demand for labor pushed up the prices of the slaves, intensifying the trade.