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Studentka2010 [4]
3 years ago
9

Potassium channel blockers (such as amiodarone and procainamide) are used to treat abnormal electrical activity of the heart. Th

ese drugs impede movement of K through voltage fated K channels. Which part of the action potential would you expect these drugs to most directly affect
Biology
1 answer:
Veseljchak [2.6K]3 years ago
8 0

Answer:

repolarization  

Explanation:

Potassium channel blockers are drugs that interfere with the flow of potassium ions (K+) through potassium channels in cell membranes, thereby prolonging the duration of the action potential (repolarization phase). For example, amiodarone is a class III antiarrhythmic agent whose target is HERG human cardiac K+ channel. This drug (amiodarone) acts by prolonging the repolarization phase of the cardiac action potential.

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The question is incomplete, it lacks the mRNA sequence. The sequence is as follows:

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Gene expression in living organisms involves the process of transcription and translation. Transcription is the synthesis of a complementary strand of mRNA from a DNA template while translation involves using the transcibed mRNA as a template to synthesize amino acid sequence (proteins).

In the RIBOSOME, where the synthesis of protein occurs, the mRNA nuceleotide sequence is read in a group of three nucleotides called CODON. Each codon specifies a particular amino acid. The collection of all codons is the genetic code. Hence, for a specific mRNA sequence that reads 5′−AUGGCAAGAAAA−3′. The nucleotides will be read three at a time starting with AUG which is a codon that encodes METHIONINE.

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