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Dennis_Churaev [7]
3 years ago
9

Tay-Sachs disease is a genetic disorder that results in the destruction of neurons due to a buildup of sphingolipids in the cell

s. Which organelle is malfunctioning in Tay-Sachs
Biology
1 answer:
m_a_m_a [10]3 years ago
7 0

Answer:

Lysosomes

Explanation:

 Tay-sachs disease is a rare Autosomal recessive disease that causes neurodegenerative disorder.

Deficiency of  an enzyme Hexosaminidase A results in excessive accumulation of gangliosides (sialic acid containing glycosphingolipids) in the brain and nerve cells.

It is a lysosomal storage disease .Absence of  the enzyme Hexosaminidase A ,that breakdowns substance like fats results in accumulation of such substance in the lysosomes.Too much accumulation of fats in the lysosomes destroy the cell.

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