Simply put, a genetic mutation comes from a change in the DNA; this change can result from an extrachromosomal element, an alteration of the inherited nucleotide...
The basic building block of nucleic acids, such as DNA and RNA. It is an organic compound made up of nitrogenous, a sugar, and a phosphate group (http://www.biology-online.org/dictionary/Nucleotide)
The surroundings or conditions in which a person, animal, or plant lives or operates.
The natural environment encompasses all living and non-living things occurring naturally, meaning in this case not artificial. The term is most often applied to the Earth or some parts of Earth.
Answer:
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Basically all of the choices given are failure of negative feedback mechanisms to maintain homeostasis. The correct option among all the options that are given in the question is the last option or option "E". I hope that this is the answer you were looking for and it has come to your help.
