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If your cartilage, muscles, or tendons put too much pressure on a nerve, it might not be able to work right. This can cause numbness. An injury or overuse can cause a pinched nerve. Sometimes it's due to health problems like arthritis, a narrowing of the spaces between the bones in your spine, or a tumor on the spine.
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They both transport ions, sugars, and salts across the membrane
Waste would start to build up in the cell since lysosomes have the role of intracellular digestion of waste materials.
A known disease that is caused by a lysosomal malfunction is Hunter's disease
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am sorry I don't know this