Autoimmune disorders are caused by different microoorganism and drug which manipulates the immune system in a way that immune system become unable to recognise between self antigen and foreign antigen. In that case immune system treats foreign antigen as self antigen which cause systemic or organ specific damage.
The exact cause of autoimmune disorders is unknown and hence it is thought that it is caused by adaptive immune response which builds against self antigens and causes damage to the cells.
Hence, some autoimmune disorders are thought to be caused by adaptive immune response.
