Answer:
1. a broken leg or arm
2. A torn muscle in the leg
Explanation:
The reason we have the Corona Virus is because some huh decided to eat a bat for some reason.
Answer:
Okay
Explanation:
Human topoisomerase I plays an important role in removing positive DNA supercoils that accumulate ahead of replication forks. It also is the target for camptothecin-based anticancer drugs that act by increasing levels of topoisomerase I-mediated DNA scission. Evidence suggests that cleavage events most likely to generate permanent genomic damage are those that occur ahead of DNA tracking systems. Therefore, it is important to characterize the ability of topoisomerase I to cleave positively supercoiled DNA. Results confirm that the human enzyme maintains higher levels of cleavage with positively as opposed to negatively supercoiled substrates in the absence or presence of anticancer drugs. Enhanced drug efficacy on positively supercoiled DNA is due primarily to an increase in baseline levels of cleavage. Sites of topoisomerase I-mediated DNA cleavage do not appear to be affected by supercoil geometry. However, rates of ligation are slower with positively supercoiled substrates. Finally, intercalators enhance topoisomerase I-mediated cleavage of negatively supercoiled substrates but not positively supercoiled or linear DNA. We suggest that these compounds act by altering the perceived topological state of the double helix, making underwound DNA appear to be overwound to the enzyme, and propose that these compounds be referred to as ‘topological poisons of topoisomerase I’
Answer:
<u><em>The answer is</em></u>: <u>Diagnostic code ICD-10-CM 2019 I50.2 Systolic (congestive) heart failure.</u>
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Explanation:
Heart failure (HF) with reduced ejection fraction <em>is responsible for approximately 50% of cases of heart failure in the U.S. and it is associated with considerable morbidity and decreased quality of life.
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<u><em>Diagnostic code ICD-10-CM 2019 I50.2 Systolic (congestive) heart failure</em></u>, applicable to Heart failure with reduced ejection fraction [HFrEF].
<u><em>The answer is</em></u>: <u>Diagnostic code ICD-10-CM 2019 I50.2 Systolic (congestive) heart failure.</u>
ANSWER:
An organization is made up of different teams that works collectively in achieving the organization aims. The performance improvement of an organization depends on the performance improvement of each team in the organization, because it is this teams that makes up the performance of the organization. The performance of this teams are also dependent on the structure of the organization, because it is the organization that equip and train each team to develop and perform excellently in a task.
Therefore for an organization performance to improve, such organization must improve the performance of each team.
