Answer:
Constitutive activation is the alteration of a protein or signaling pathway such that it is functional or engaged even in the absence of an upstream activating event. For example, RasD is constitutively active because it cannot bind GAP and therefore remains in the GTP-bound, active state even when cells are not stimulated by growth factor to activate a receptor tyrosine kinase.
Constitutively active Ras is cancer promoting because cells will proliferate in the absence of growth factors, and thus normal regulatory mechanisms for cell proliferation are bypassed.
(a) A mutation that resulted in Smad3 binding Smad4, entering the nucleus, and activating transcription independent of phosphorylation by the TGFβ receptor would render Smad3 constitutively active.
(b) A mutation that made MAPK active as a kinase and able to enter the nucleus without being phosphorylated by MEK would render MAPK constitutively active.
(c) A mutation that prevented NF-KB from binding to IK-B or that allowed NF-KB to enter the nucleus and regulate transcription even when bound to IK-B would render NF-KB constitutively active.
A) 3,5,1,6,2,4 is the correct order for the events of protein synthesis.
<h3>What is protein synthesis?</h3>
Protein synthesis (translation) is the process of creating a polymer of an amino acid chain that results in the production of a functional protein. It entails reading information from mRNA (messenger RNA) and assembling an amino acid chain. Ribosomes are the structures responsible for protein chain synthesis.
Protein synthesis is an important process because we rely on our bodies to build the proteins we require to perform important functions. Without protein synthesis, our bodies will be unable to produce hormones, enzymes, and even new muscle.
Learn ore about protein synthesis, here:
brainly.com/question/16305501
#SPJ1
Answer: The statement is false
Explanation:
Addition of concentrated sulfuric acid (H2SO4) to a beaker full of water (H2O) will release heat energy to the containing vessel due to the breakage of strong ionic bond present in the acid.
Thus, it is an evidence of a EXERGONIC REACTION (since energy is released spontaneously). So, the statement is false
Meiosis plays a role in reproduction.
