“EPSP” means “excitatory postsynaptic potential” which occurs when +ively charged ions move towards the postsynaptic cell thereby depolarizing of postsynaptic membrane potential. IPSPs are inhibitory postsynaptic potential. Whenever the EPSPs or IPSPs changes, the , neurotransmitters bind to receptors thereby opening or closing ion channels in the postsynaptic cell and hence triggering the Action potentials which is basically nerve impulses or spikes.
