Beta-globin is a component (subunit) of a larger protein called hemoglobin, which is located inside red blood cells. In adults, hemoglobin normally consists of four protein subunits: two subunits of beta-globin and two subunits of another protein called alpha-globin, which is produced from another gene called HBA.
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sciencebiologybiology questions and answersConcentration Of NAD+ (umol/L) 4 8 12 16 20 Concentration Of Lactic Acid (mmol/L) OHHHHHHHHHHHHHHHHHHHH...
Question: Concentration Of NAD+ (umol/L) 4 8 12 16 20 Concentration Of Lactic Acid (mmol/L) OHHHHHHHHHHHHHHHHHHHH 4 8 12 16 20 Time (weeks) Figure 2. The Concentration Of NAD* (top) And Lactic Acid (bottom) In The Blood Of A Representative Treated Individual (a) Describe The Pattern Of Inheritance That Is Most Likely Associated With A Mutation In The MT-ND5 Gene. ...
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Concentration of NAD+ (umol/L) 4 8 12 16 20 Concentration of Lactic Acid (mmol/L) OHHHHHHHHHHHHHHHHHHHH 4 8 12 16 20 Time (we
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Concentration of NAD+ (umol/L) 4 8 12 16 20 Concentration of Lactic Acid (mmol/L) OHHHHHHHHHHHHHHHHHHHH 4 8 12 16 20 Time (weeks) Figure 2. The concentration of NAD* (top) and lactic acid (bottom) in the blood of a representative treated individual (a) Describe the pattern of inheritance that is most likely associated with a mutation in the MT-ND5 gene. Explain why individuals are not typically heterozygous with respect to mitochondrial genes. (b) Identify a dependent variable measured in the researcher's experiment. Identify one control that the researcher could use to improve the validity of the experiment. Justify the researcher analyzing blood samples at many intermediate time points instead of at only the beginning and the end of the 20-week period. (c) Describe the relationship between the concentration of NAD in the blood and the concentration of lactic acid in the blood during the first 5 weeks of treatment with the vitamin. Based on Figure 2, calculate the average rate of change in blood NAD concentrations from week 5 to week 17. (d) The researcher performed a follow-up experiment to measure the rate of oxygen consumption by muscle and brain cells. Predict the effect of the MT-ND5 mutation on the rate of oxygen consumption in muscleand brain cells. Justify your prediction. The researcher had hypothesized that the addition of the vitamin that is similar in structure to NADH would increase the activity of the mutated NADH dehydrogenase enzyme in individuals
