1answer.
Ask question
Login Signup
Ask question
All categories
  • English
  • Mathematics
  • Social Studies
  • Business
  • History
  • Health
  • Geography
  • Biology
  • Physics
  • Chemistry
  • Computers and Technology
  • Arts
  • World Languages
  • Spanish
  • French
  • German
  • Advanced Placement (AP)
  • SAT
  • Medicine
  • Law
  • Engineering
kolezko [41]
3 years ago
9

Why is it essential for SARS-CoV2 RNA be translated on ribosomes before it can be replicated?

Biology
1 answer:
Natalka [10]3 years ago
5 0

The SARS-CoV-2 non-structural protein 1 (Nsp1), also referred to as the host shutoff factor, suppresses host innate immune functions. By combining cryo-electron microscopy and biochemistry, we show that SARS-CoV-2 Nsp1 binds to the human 40S subunit in ribosomal complexes, including the 43S pre-initiation complex and the non-translating 80S ribosome. The protein inserts its C-terminal domain into the mRNA channel, where it interferes with mRNA binding. We observe translation inhibition in the presence of Nsp1 in an in vitro translation system and in human cells.

You might be interested in
Using a pyramid of numbers explain why herbivores are so important in maintaining a balance in the ecosystem.​
attashe74 [19]
Herbivores are close to the bottom of the pyramid, which means that other animals (carnivores) rely on them to eat the plants, stay alive, and then eat them as their own food, which then the cycle continues
8 0
3 years ago
What body parts help a tiger shark live in the ocean?
brilliants [131]
Its Fins, gills, and tail are all crucial for a sharks survival
3 0
4 years ago
Whoever answers first get real brainiest
den301095 [7]

Answer:

IDEK

Explanation:

IM STUCK TOO SOMEONE HELP!

5 0
3 years ago
Where does most of the metabolic activity in the cell occur? cytoplasm DNA cell wall nucleus
AveGali [126]
The most of the metabolic activity in the cell occur in the cytoplasm
6 0
3 years ago
Suppose a researcher introduces a mutation into the glucosidase domain of the mammalian glycogen debranching enzyme. The mutatio
Anestetic [448]

Answer:

c. glycogen molecules with branches containing a single glucose residue

Explanation:

The mutation inhibits the activity of the glucosidase but does not affect the other functions of the enzyme. The researcher then introduces the mutated enzyme into mammalian cells that do not express wild type glycogen debranching enzyme because glycogen molecules with branches containing a single glucose residue (single glucose molecule linked by alpha 1,6 linkage due to mutation in glucosidase activity of debranching enzyme).

3 0
4 years ago
Other questions:
  • How are the parts of dna like a book?
    13·2 answers
  • What is the best explanation for why scientists involved in biotechnology sometimes insert the DNA of one organism into a second
    13·1 answer
  • Change in the genetic make-up, appearance, and behaviors of a species over time is called
    14·1 answer
  • How many ways are there for carbon to get transported to the atmoshpere
    7·1 answer
  • What is the physiological significance of the presences of myelin on an axon?
    10·1 answer
  • What the differences between reproductive system and reproduction?​
    5·1 answer
  • Fermentation has a relatively low ATP yield compared to aerobic respiration because a. more reducing equivalents are used for an
    9·1 answer
  • (this is my own question that i know the answer to im a equstrian with 2 horses ok) there is a boy horse a man horse and a femal
    11·2 answers
  • What causes Sadness.<br>Does it affect our body?.<br>さようなら頭のいいお母さん。​
    5·1 answer
  • If a fox and an eagle eat some of the same organisms in an ecosystem, the relationship between the fox and the eagle could be cl
    11·1 answer
Add answer
Login
Not registered? Fast signup
Signup
Login Signup
Ask question!