Histone deacetylase is responsible for removing the acetyl group from the histone 3 lysine 9 residue. Remember that deacetylation is one step in converting euchromatin to heterochromatin. Because euchromatin is transcriptionally active (transcriptional machinery is able to reach gene of interest), and blocking histone deacetylase activity would result in an the DNA remaining as euchromatin, we would expect to see an increase in transcriptional activity.
So there’s your answer: An increase in transcriptional activity.
Answer: In Spanish
¿Cómo se vuelven resistentes las bacterias a los antibióticos?
R: Las bacterias pueden volverse resistentes a los antibióticos de varias maneras. Algunas bacterias pueden "neutralizar" un antibiótico cambiándolo de una manera que lo hace inofensivo. Otros han aprendido a bombear un antibiótico fuera de la bacteria antes de que pueda causar algún daño. Algunas bacterias pueden cambiar su estructura externa, por lo que el antibiótico no tiene forma de adherirse a la bacteria que está diseñada para matar.
Después de exponerse a los antibióticos, a veces una de las bacterias puede sobrevivir porque encontró una manera de resistir el antibiótico. Si incluso una bacteria se vuelve resistente a los antibióticos, puede multiplicarse y reemplazar todas las bacterias que fueron eliminadas. Eso significa que la exposición a los antibióticos proporciona una presión selectiva que hace que las bacterias sobrevivientes sean más propensas a ser resistentes. Las bacterias también pueden volverse resistentes a través de la mutación de su material genético.
Answer in English :
How do bacteria become resistant to antibiotics?
A: Bacteria can become resistant to antibiotics through several ways. Some bacteria can “neutralize” an antibiotic by changing it in a way that makes it harmless. Others have learned how to pump an antibiotic back outside of the bacteria before it can do any harm. Some bacteria can change their outer structure so the antibiotic has no way to attach to the bacteria it is designed to kill.
After being exposed to antibiotics, sometimes one of the bacteria can survive because it found a way to resist the antibiotic. If even one bacterium becomes resistant to antibiotics, it can then multiply and replace all the bacteria that were killed off. That means that exposure to antibiotics provides selective pressure making the surviving bacteria more likely to be resistant. Bacteria can also become resistant through mutation of their genetic material.
I don't know if this help you at all.
Explanation:
Nondisjunction: Failure of paired chromosomes to separate (to disjoin) during cell division, so that both chromosomes go to one daughter cell and none go to the other. Nondisjunction causes errors in chromosome number, such as trisomy 21 (Down syndrome) and monosomy X (Turner syndrome). It is also a common cause of early spontaneous abortions
It will get lower since the pressure around the barometer gets lower
<span>This theory is called punctuated equilibrium. In this theory it is explained that there are very long periods of no change at all to a species, yet there are also bursts of evolutionary change interspersed within the time period. The period of remaining the same throughout time (most of the time) is called stasis, and is present within this theory of punctuated equilibrium.</span>
