<span>Two checkpoints during the cell cycle that regulate cell division are right before S phase and M phase.
</span>Cell cycle checkpoints are control mechanisms <span>necessary for proper cell division. </span><span>In the cell cycle, there are two checkpoints: </span><span>the G1 checkpoint and the G2 checkpoint. <u>The G1 checkpoint is right before the S phase, and G2 checkpoint is right before the M phase.</u>
If something is wrong at the G1 checkpoint, the cell will not enter the cell cycle. It is important to be delayed before cell enters S phase where DNA replication commences.
The G2 checkpoint is a DNA damage checkpoint and if DNA is damaged, entering the cell cycle is delayed before mitosis (M phase).</span>
From these observations, the researcher may use bottom up approach to suggest that the blood clotting properties of COX-2 inhibitors lead to heart failure.
Heart failure occurs when the heart muscle doesn't pump blood as well as it should. Blood often backs up and causes fluid to build up in the lungs (congest) and in the legs. The fluid buildup can cause shortness of breath and swelling of the legs and feet. Poor blood flow may cause the skin to appear blue (cyanotic).
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60% of animal life live in oceans
The cell membrane controls what enters and exits the cell.